Questions and answersProduct application
How often should advantix be applied?Monthly treatment with advantix provides excellent control and prevention against ticks, fleas, sand flies and mosquitoes. In particular cases of high parasite pressure or during seasons, the frequency of treatment may be increased as far as once weekly. How long after application does advantix "dry out"? The product appears to be oily and to form an oily damp stain which takes some time to resolve.The vehicle of advantix, which binds to and carries imidacloprid and permethrin, is organic and of an oily appearance (unlike Advantage in which it is alcoholic); its distribution on the body surface of the dog depends on: Is advantix distributed in the same way and as speedily as Advantage?Pharmacokinetic studies carried out with advantix have shown that the distribution of imidacloprid across the surface lipid film is faster than that of permethrin: distribution is complete within 12 to 24 hours for imidacloprid and within 24 to 48 hours for permethrin. Can advantix be used together with other repellent products such as citronella?advantix is registered for use on dogs. It has a considerable repellent effect and this can be increased by reducing the interval between applications. Can advantix be used concomitantly with ivermectin?advantix has been tested on a very large number of dogs. Many of these had undergone many treatments and prophylactic measures, including treatment for cardiopulmonary filariasis based on various active substances including ivermectin. No adverse effects or toxicity due to these combinations has ever been observed. Can advantix be used to control scabies?advantix has not yet been tested against these parasites. One may however presume that it may have an effect on sarcoptic and (perhaps) otodectic scab mites. It is unlikely however to be efficacious on demodectic scabies simply because of the intrinsic features of this parasitosis. Can advantix be used to control flies?advantix has not yet been tested against these parasites. One may however presume that it may have a repellent effect against flies in general. Can advantix be used to control parasitic diseases of reptiles?advantix has not been tested against parasitoses in these animals. Can advantix be used to control parasitic diseases of rabbits and ferrets?advantix is not toxic for topical use in rabbits (LD50 2000 mg/kg) or in rats (5000 mg/kg), and presumably this toxicity is similar for ferrets. It is also very likely that advantix may be efficacious on parasites in these animals as well. Generally speaking it should however be considered that these animals are mostly exposed to infestations by fleas only and that a product like Advantage will therefore be sufficient. |
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